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Notably, these findings are largely in line with those from a real-world temporal analysis similarly characterizing SGLT2i and GLP-1 RA new users in Japan between the same two time periods [22]

By sensing the luminal milieu, neuroendocrine cells of the intestines, namely, enteroendocrine cells, release peptides that serve as regulators of glucose homeostasis, including GLP- 1 and cholecystokinin [42]

Those with kidney or gallbladder disease need careful monitoring

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1 A separate variant in the GIPR gene predicts nausea and vomiting specifically in people taking tirzepatide (Mounjaro and Zepbound), but not in people taking semaglutide (Wegovy and Ozempic)

These injuries refer to partial or complete damage to the tendons, muscles, and ligaments, which may or may not require surgical repair